MTHFR (methylenetetrahydrofolate reductase) Mutation Test

Description

WHAT IS THE MTHFR MUTATION LAB TEST?

This is a blood test for the MTHFR Genetic Mutation.

WHAT IS THE PRICE FOR THE MTHFR MUTATION TEST?

*Price may vary by location – contact your local ANY LAB TEST NOW®

DESCRIPTION:

The human body contains 20,000 genes, one of which is the MTHFR gene. Most people have two copies of it. The MTHFR gene is responsible for instructing the body on making methylenetetrahydrofolate reductase, an enzyme that is used to metabolize folic acid (B9) into methyl-folate, folate’s active form. Methyl-folate plays a critical role in the proper functioning of numerous bodily systems including:
• Repairing and regenerating your cells, tissues and DNA
• Regulating gene expression and protein function
• Synthesizing neurotransmitters that influence mood, sleep, behavior, cognition and memory
• Controlling homocysteine, an amino acid that at high levels is associated with cardiovascular disease, stroke and thrombosis.
• Reduces the inflammatory process
• Assisting your liver to process fats
• Activating and regulating the immune system
• Modifying toxins and heavy metals

WHY DO I NEED TO I NEED THE MTHFR GENETIC MUTATION LAB TEST?

Some people have a mutation of the MTHFR gene that causes defective MTHFR enzymes. The defective enzymes cause the body to produce up to 70% less methyl-folate and reducing the effectiveness of many normal body processes.
This test is recommended for those with high homocysteine levels, a family history of cardiovascular disease, stroke or thrombosis, a close relative with a known MTHFR mutation or those who are candidates for long-term methotrexate therapy. The test results may identify serious illnesses and complications caused by an MTHFR genetic mutation. It may be ordered with other inherited clotting risk factor tests such as the Factor V Leiden or Prothrombin Factor II mutation tests to help determine a person’s risk of developing dangerous blood clots.

TEST DETAILS:

MTHFR Test results are typically reported as negative or positive and, if positive, the report will name the mutation(s) present. Often, an interpretation of the results is also provided.

WHAT TYPE OF PHYSICIAN SHOULD I SEE IF MY TEST RESULTS ARE POSITIVE?

You should see your primary care physician or a hematologist.